Chorioretinitis can be caused by which categories of disease?

Chorioretinitis can be caused by which categories of disease?

• A. Infectious, neoplastic, immune-mediated/inflammatory
• B. Trauma alone
• C. Degenerative myopia only
• D. Nutritional deficiency only

Answer: (A)

Chorioretinitis is inflammation of both the choroid and retina, and it can arise from a range of disease processes. The best-fitting categories are infectious causes (for example toxoplasmosis, syphilis, tuberculosis), immune-mediated or inflammatory diseases (such as sarcoidosis or sympathetic ophthalmia), and neoplastic involvement (like intraocular lymphoma or choroidal metastases) that provoke inflammatory-appearing changes in these tissues. Other options don’t typically cause true chorioretinitis: trauma leads to mechanical injury, degenerative myopia causes degenerative changes rather than inflammatory choroid/retina inflammation, and nutritional deficiencies cause various retinopathies that are not defined by chorioretinitis.

Chorioretinitis is inflammation of both the choroid and retina, and it can arise from a range of disease processes. The best-fitting categories are infectious causes (for example toxoplasmosis, syphilis, tuberculosis), immune-mediated or inflammatory diseases (such as sarcoidosis or sympathetic ophthalmia), and neoplastic involvement (like intraocular lymphoma or choroidal metastases) that provoke inflammatory-appearing changes in these tissues.

Other options don’t typically cause true chorioretinitis: trauma leads to mechanical injury, degenerative myopia causes degenerative changes rather than inflammatory choroid/retina inflammation, and nutritional deficiencies cause various retinopathies that are not defined by chorioretinitis.